Technology

ComboCap® technology allows for separate ingredients to be housed in a single 2-in-1 product. Never before has ingestible product delivery been this convenient with the added potential of boosted bioavailability, greater stability and the promise of creating pioneering substance combinations.

YEARS IN THE MAKING

The ComboCap® technology has been developed and successfully patented over a period of 7 years by internationally acclaimed scientists and researchers. It has been designed to provide a new and exciting way in which to deliver dietary supplements, medicines, or other health and wellness products to consumers.

THE LATEST DUAL DELIVERY
CAPSULE PRODUCT TECHNOLOGY

ComboCap® is a simple, robust, dual-compartment capsule product currently available in the “00” size. It is made of standard capsule-grade bovine or fish gelatin or vegetarian material. The patented domed diaphragm of the same specification is fused into place using a patented, high-tech process.

WE UPHOLD THE HIGHEST STANDARDS

The ComboCap® can carry 320mg to 500 mg of fish oil or equivalent liquid (0.97sg) and 250mg to 400 mg of dry powder, granulated powder or beadlets. The sealed primary compartment is liquid filled and sealed on a specialized fill-and-fuse line. The secondary filling is executed on a standard powder capsule filling line.

IN HONOR OF DESIGN ELEGANCE

The entire capsule and diaphragm are comprised of pharma-grade bovine or fish gelatin or vegetarian materials. The primary compartment is leak-proof and flushed to prevent oxidation of the primary ingredients. The domed diaphragm is coalesced after filling using a patented, ingenious fusion process. A patented vacuum filling process is used to achieve the diaphragm fill-and-fuse process. This process produces a pressure-neutral, primary compartment for enhanced integrity.

CUSTOMER DRIVEN ROLLOUTS

The primary compartment can take both compatible wet or dry ingredients and the secondary compartment is currently for dry ingredients only, in the first generation production line. The capability for other combinations of ingredients will be developed to suit customer formulations and emerging dual-dose medicines.

ATTENTION TO THE FINEST DETAILS

Primary filling is executed on a patented filling line and secondary filling on approved standard high-speed lines. Hard capsule oxidation is significantly lower than with soft gels. This is a critical benefit for oil based ingredients.

How it Works

Moveable Membrane

The diaphragm, which separates the two compartments of the patented ComboCap, is a revolutionary breakthrough that allows previously nonviable combinations to be delivered simultaneously. The volume of ingredients in either side of the product is determined by the client’s approved formulation as well as the predetermined volume limitations stipulated by ComboCap.

Various liquids, including oils, can be contained within a ComboCap product together with other active ingredients. This allows for a single capsule to deliver multiple ingredients, resulting in an unprecedented level of convenience and an innovative product delivery.

Dual-Delivery Product

Research has shown that water and fat based liquids are often necessary for the proper absorption of active ingredients in the digestive system. By providing these components in the liquid portion of the capsule products, the bioavailability of the key ingredients can be considerably improved. And the more bioavailable a product is, the greater its beneficial effect on the body. As a result, lower dosages may be required, side effects are potentially reduced and the efficiency of delivery is substantially boosted.

Proprietary Process

As the demand for the innovative ComboCap® system continues to escalate, ComboCap, Inc. will help leading companies experiment with new formulations. This could potentially extend to the ComboCap technology becoming a preferred delivery system for some combination therapies.